How to write a cover letter for grad school, post doc, job positions

 

Dear Members of the Search Committee,

Give a quick overview: I am writing to express my interest in the doctoral program/post doctoral position/---- position in focus area of --- and ---- as bio-nanoparticles, genomics, and gene delivery. Currently, I am a ---- of genetics and genomic sciences, and pathology at -----. Two years into my appointment, I have laid the foundation of my proposed research project that I plan to develop on 1) ; 2) Genomics & bioinformatics; and 3) . My proposed research program is founded on the work that I have recently published/ patented (US Patent 2020). This work describes, for the first time, that exosomes can be engineered, made tissue-tropic, and effectively deliver its genetic and proteomic cargo. This project is highly relevant to this position, as my goal is to develop exosomes for effective gene delivery to the heart.

Future Goals: Talk about your My primary research goal is to develop precision nanomedicines for clinical use. For instance, I would like to develop a research program that addresses the extracellular biology of benign and cancer cells by studying their exosomes’ DNA, RNA, and proteins. Furthermore, I would like to characterize the complete secretome of the diseased cell (pre and post drug exposure), given that exosomes are only a subset of the vast extracellular canopy. The cellular secretome is a concept I introduce here to embody the compendium of circulating particles (microvesicles, exosomes, lipoproteins, ribonucleic protein, and free DNA/RNA/protein) that link the intercellular communication. To accomplish this objective, I will use the technology that I have developed to isolate all extracellular particles from different cell culture media and various biofluids (serum, urine, plasma) . My long-term goal is to understand the fundamental and applied biology of the cellular secretome, and my success will not only delineate the uncharacterized extracellular biology but will also lead to next generation liquid-biopsy and gene delivery applications.

Training: Prior to Mount Sinai, I was trained at ----Center (in genomics & bioinformatics of exosomes) and --- University (in biomedical engineering of vesicles). I will take advantage of my training to address the major unanswered questions in the field of liquid-biopsy and gene delivery. My past research training and strong publication record has positioned me well to develop a unique research program that integrates wet lab with dry lab. Overall, my goal is to foster a dynamic scientific exchange by developing an interdisciplinary research program, while keeping exosomes and genomics at the center of my discoveries. 

I will contribute to the growth of the department’s research and teaching, especially with my chemistry, bioengineering, genomics, and bioinformatics skills. I look forward to contributing to and learning from the faculty members of your esteemed institute. Thank you for considering my application.

Sincerely, 

How to write a cover letter

Here is a simple but striking cover letter. Remember, keep you cover letter short and succinct.

Cover Letter

November, ……, 2012

Editor

The New Yorker

4 Times Square

New York, NY 10036

Dear Editor.

I am a ………student at …………University and would like to be considered for a ……..opportunity at The New Yorker. I am very interested in the field of science and political cartooning. I would welcome the opportunity to contribute my cartoons and writing skills to your highly regarded organization.

I am very excited about The New Yorker’s commitment toward cartoons and science. As a cartoonist for my university’s new paper, and as a science researcher, I am very aware of importance of making science, interesting to general audiences.

At….., my concentration is in …….while also exploring journalism by working at ……news paper. My research is further established by my recent publications appeared on …..major scientific journals. On the other front, I have enjoyed cartooning and writing for ……. since 2008.

Thank you for your consideration. I very much look forward to the opportunity to speak with you in person about my interest on publishing my woprk on The New Yorker.

Sincerely,

………..
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Statement of purpose for Mathematics, Physics ans Statistics

Mathematics has always been my passion and obsession since my childhood. It always occupied most of my time and I never had any ambition in my life other than being a research mathematician.
I was introduced to mathematics at an age as early as two years through basic arithmetic operations. When I grew older to enter primary school I was haunted by the questions like what is addition and what is subtraction etc. I was not at all happy with the basic school level idea of computing the sum for two given numbers. I started asking the question to myself, what is a number. The non-rigorous nature of school level mathematics always pained me and I tried to have my own way of defining mathematical concepts for myself, which I came to know to be true later. When I was introduced to Euclidean Geometry, the book told me the conditions when two triangles are congruent. But it never told when two figures in a plane are called congruent. So I defined congruence for myself, and in the process I conceived the notions of isometry and equivalence relations. This way I always tried to rigorize the elementary mathematics. While leaving school I had developed my keen interest on number theory also.

In the penultimate year in my high school, I took part in Regional Mathematical Olympiad-about ten thousand students took that test-and got selected for participation in Indian National Mathematical Olympiad. I also took part in several mathematics talent search examination that is widely taken by almost all school kids nowadays. And I never achieved anything except the top grade. I also took part in several national level quiz competitions and represented my state. I also received the top grade in Australian Mathematics Competition, in which students from all the countries participated.

After completing fourteen years of schooling I joined the Indian Statistical Institute (I.S.I) as an undergraduate student in 1997 and completed Bachelor of Statistics (Honors), a three years undergraduate course. After passing Bachelor of Statistics (Honors) with First Division in 2000, I joined the Master of Statistics - a two years Masters program. I am presently in my final year of Master of Statistics doing advanced courses in Mathematics. I.S.I is an Institute of National Importance in India and reputed for its high quality teaching and research in Mathematics, Statistics and Probability. Entry to I.S.I is a highly competitive business. Selection is done through a nation wide examination on mathematics followed by an interview by the I.S.I faculty. This selection carries substantial financial support apart from the tuition waiver all through the undergraduate years and the two years of masters. Besides the stipend we are provided with other facilities like contingency grant etc. I.S.I. is the only institute in the country that provides financial support for the undergraduates and hence the competition involved at the entry point is very keen.

In I.S.I., I got interested in Probability Theory and Analysis. I received a very strong and rigorous training in both analysis and probability theory. My advanced courses in analysis include courses on functional analysis, Fourier analysis on locally compact abelian groups and Brown-Douglas-Fillmore Theory. And as for probability I have been exposed to training in Brownian motion, Martingale Theory, Markov Processes, Diffusion Theory and Stochastic Calculus. I got interested in Differential Geometry when I was trying to understand the structure of Möbius Strip, whose non-orientability drew my attention. Then I visited our Bangalore Center to start my study on Differential Geometry under Prof. V. Pati. Then subsequently I visited the School of Mathematics of Tata Institute of Fundamental Research (T.I.F.R) (the national center of the Government of India for Mathematics and nuclear Science) twice to take part in Visiting Students’ Research Program (V.S.R.P.) where I worked with Dr. Pablo A. Gastesi on Differentiable Manifolds and Lie Groups. During my next visit to T.I.F.R. I worked with Prof. T. N. Venkataramana on Analytic Number Theory. I also attended acourse on Set Theory meant for fthe Doctoral students. While continuing my study on Differential Geometry I felt that I should have some knowledge of Algebraic Geometry also. So I started to learn Commutative Algebra and subsequently Algebraic Geometry also. This year I took part in International Conference on Algebra and Geometry held during 7th to 12th December 2001 at University of Hyderabad. I was the only student invitee in that conference. I am also attending the Workshop on Operator Theory and Operator Algebra in Indian Statistical Institute, Bangalore.

Presently I am working on deriving some known properties of Riemann zeta function using some probabilistic techniques, and metrizing certain class of figures in the plane and looking at the convergence of shapes. And also I am reading some materials about Brownian motion on smooth manifolds.

Throughout my student life I had also given a lot effort to extra-curricular activities also. I have been playing violin for quite a few years from now. I have always been interested in poetry also and have been publishing them from time to time. I have also borne the responsibility of editing a few magazines on literature and science awareness. I have been also acting in several stage performances of plays and audio-dramas from my childhood.

I have also put great effort in order to teach mathematics at elementary level in a rigorous fashion. I have been the in-charge of the mathematics cell of an organization that is involved in science awareness. Thus teaching has always been of great pleasure to me. I carried out several training camps in mathematics and many of my students performed excellently in Regional and National Mathematical Olympiads. And my background in acting has always enhanced my skill of presentation. I have also given several student seminars in my institute, which were widely appreciated. The topics of my seminar include Differential Geometry, Analytic Number Theory, Measure Theory and many more. But learning mathematics for myself has always remained at the center of my attention.

Apart from having the requisite background, I am confident that my dedication, hard work and strong will to achieve success will help me create a niche for myself in the areas of my interest. I am also confident that I will be able to meet the demands and requirements of the graduate courses and research work in your department. I hope to pursue a career in research in mathematics, and eventually contribute significantly to this branch of knowledge.

Thank you very much for considering my application.